About the role:   We are seeking an outstanding Mechanical Engineer 3, Consumables Sustaining to join the Manufacturing Systems Engineering (MSE) team at 10x Genomics. This is a key position for the sustainment and technical stewardship of on-market consumables products. This is a multi-disciplinary position that involves close collaboration with various groups including other operations functions (Supply Chain Management, Planning, Manufacturing, Quality Control) as well as Fluidics and R&D Engineering. You will play a key role in driving and supporting issue identification, root cause analysis and remediation.   The ideal candidate will have a proven track record in supporting complex plastic components for the life sciences or medical device industries. They should possess a broad understanding of the design and manufacturing of complex plastic systems and excel in solving complex problems. As a member of the team, you will be instrumental in supporting 10x manufacturing, supply chain, and service & support teams to support products that enable accelerated understanding of biology. What you will be doing: 1. CROSS-FUNCTIONAL COLLABORATION  * Support the design, development and transfer of new consumable components. * Serve as mechanical point of contact for on-market consumables sustaining issues. * Communicate findings and recommendations to cross-functional stakeholders across operations, commercial and R&D. 2. ROOT CAUSE ANALYSIS AND SUSTAINING DESIGN * Troubleshoot and resolve both field and manufacturing issues with consumables (e.g. LSR-thermoplastic assemblies and precision injection-molded COC/COP microfluidics). * Lead/support root cause investigations (e.g. seal leaking, dimensional drift, biocompatibility, cracking) using FEA, tolerance analysis and hands-on failure analysis. Implement and verify corrective actions. * Support investigations into fluidic and microfluidic performance issues in partnership with broader sustaining and R&D engineering groups.  3. MANUFACTURING AND QUALITY SUPPORT * Drive on-market engineering changes (ECOs/ECRs) through change control process. * Contribute to CAPAs, non-conformance investigations and support QC method development and deployment. * Utilize Arena PLM and Oracle ERP systems to manage product lifecycle and manufacturing processes effectively. 4. CONTINUOUS IMPROVEMENT * Identify yield, reliability and quality improvement opportunities for on-market consumables. * Support Gage R&R, FMEA and risk assessment of on-market consumable issues. MINIMUM REQUIREMENTS: * Education: BS/MS in Mechanical Engineering. * Experience: 6+ (BS) or 4+ (MS) years of experience in mechanical design or sustaining engineering, with at least 3 years specifically in biotech consumables. * Plastics Expertise: Demonstrated knowledge and experience with thermoplastic resins (COC, COP, PC, PP), elastomers (TPE/TPU), and the nuances of precision injection molding. * Engineering: Strong understanding of 3D mechanical design, geometric tolerancing per ASME Y14.5, dimensional stack-ups and inspection procedures. * Tooling/Equipment: Demonstrated proficiency with CAD, PDM systems, simulation suites, metrology and imaging equipment (e.g. OGP, Keyence, Nikon) and data analysis tools (e.g. JMP). * Quality Systems: Familiarity with Risk Management, Process capability (cpk, ppk), FMEA, and Gage R&R. #LI-MH1 Below is the base pay range for this full-time position.  The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience.  At 10x, base pay is also just one component of the Company’s total compensation package.  This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program.   During the hiring process, your 10x recruiter can share more about the Company’s total compensation package. Pay Range $126,700—$171,500 USD Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law. 10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee. Please be aware of recruitment scams impersonating 10x Genomics. All recruiting communication will come from email addresses @10xgenomics.com [http://10xgenomics.com]. We also want to encourage you to apply to 10x Genomics positions directly on our careers site, https://careers.kula.ai/10xgenomics?pid=171812447059&domain=10xgenomics.com [https://careers.kula.ai/10xgenomics?pid=171812447059&domain=10xgenomics.com] or from reputable third party sites, such as LinkedIn or Indeed. We will never request payment or sensitive personal information during the recruiting process.